Growth hormone (GH) is a protein hormone secreted by the pituitary gland which stimulates growth and cell reproduction. Growth Hormone Releasing Hormone (HGHRH) and Somatostatin (SST) are released by the hypothalamus, and that determines whether more or less HGH is produced by the pituitary. Many factors influence the release of HGH, however, including nutrition and exercise.
In the past growth hormone was extracted from human pituitary glands. GH is now produced by recombinant DNA technology, and prescribed for a variety of reasons. GH therapy has been a focus of social and ethical controversies for 50 years.
Once it is released, Human Growth Hormone (HGH), which is also called Somatotropin (STH) has many functions in the human body. HGH is a protein that stimulates the body cells to increase both in size, as well as undergo more rapid cell division than usual. In addition, it enhances the movement of amino acids through cell membranes and also increases the rate at which these cells convert these molecules into proteins. Clearly, you can see that this would amount to an anabolic (muscle building) effect in the human body. HGH also has the ability to cause cells to decrease the normal rate at which they utilize carbohydrates, and simultaneously increase the rate at which they use fats. Fat loss and lean mass increases with HGH have been found at a dose as low as . 0.028 iu/kg/daily for 24 weeks.
Although HGH can easily produce very nice, high quality weight and muscle gains, it´s a very poor compound for inducing strength gains. That´s very counterintuitive, and certainly many strength athletes have experienced great results in strength as well as muscle size and fat loss from HGH. Generally, many studies have focused on HGH vs. HGH and exercise, and without the exercise LBM increases but not usually maximum voluntary strength output. It should also be noted that most athletes utilizing HGH are using it in a "cocktail" with (at least) anabolic steroids, and usually with IGF, thyroid meds, and other goodies such as an Aromatase Inhibitor(Tamoxifen, Arimidex, Aromasin etc.)
Most people who are taking the plunge into HGH use have reached a dead end with their use of anabolics, and need to push through that wall. I´m sure you´ve heard about the synergistic combination of using HGH along with Anabolic Steroids, IGF, insulin and T3 ( usually synthroid, a thyroid medication). The reason is that when these hormones are used correctly together, they´ll produce a large amount of synergy, the insulin is able to shuttle nutrients into your muscle, the thyroid hormone increases your fat-burning capability, the IGF will cause muscle growth as well as helping to grow new cartilage (thus preventing injury), and the anabolic steroids like testosterone, specifically (in addition to being anabolic) can increase IGF-1, in muscle tissue, and maybe even increase your body´s ability to use it. Also, usually, an increased amount of IGF usually tells your body to stop producing HGH, but testosterone actually blunts this part of the Negative FeedBack Loop! And the addition of an Aromatase Inhibitor will also stop conversion of testosterone into estrogen; estrogen reduces IGF levels.
Thus, IGF, Testosterone (and of course other steroids), Insulin, thyroid meds, and HGH will all combine to produce a pretty damned effective fat-burning and muscle building cycle! You know what else? HGH is virtually undetectable on any sort of currently used drug-screening tests. HGH, Insulin, Thyroid meds, and IGF may also be used pretty safely by those who may be subject to drug screening tests, or as a non-HPTA suppressive "bridge" between cycles.
I feel very comfortable speculating that the use of HGH in this manner, which more closely simulates the natural secretion pattern of it, allows the HGH receptors and the rest of the body to more efficiently recover from it, and this will result in much more muscle growth over time (although height was examined in the previous study). My recommendations therefore are 2 shots per day of .028iu/kg of bodyweight, taken every other day, for a minimum of 3months, and preferably for 2-3x that long, and preferably with the other synergistic compounds we´ve just taken a look
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