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Pharmacokinetics and Indications: Methandienone is an anabolic steroid banned from use by FDA under controlled substances act. It has been very popular in bodybuilders until its ban to increase strength and volume of their muscles. Methandienone acts strongly on androgen receptors and exerts its effects by protein synthesis and glycogen breakdown to increase muscle mass in short space of time. It produces estrogen as end product so water retention is also one of the contributors towards weight gain and increased volume. Its effective dose is15-50 mg/day in men and its active life is 6-8 hours. It is excreted through kidneys and detection time in urine is 5-6 weeks. Until the ban it has been used as tonic by bodybuilders. Probably, it is effective in treatment of senile postmenopausal osteoporosis. It was also recommended in those individuals who are suffering from condition called pituitary deficient dwarfism. It was also used in those individuals who have weakened bones and always complain for exhaustion after small running and prolong walking. Still, it is prepared in large quantity in those countries where drugs regulations are weak and is used in human as well as in veterinary patients of the conditions described above.
Possible Side effects: There are several side effects of this steroid such as Gynacomastia is always concerned in the patients use this regularly. Skin could become oily and hairs can grow on face and body. Virilization of the female such as deepness in the voice, irregularities in the menstruation, alteration in the texture of the female skin and enlargement of clitoris may occur by its usage. Prolong intake to this medicine may lead to hepatotoxicity.
Effective dose: 10 - 100 mg per day
Use for: 4 - 6 weeks
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